Searchable abstracts of presentations at key conferences in endocrinology

ea0016p165 | Comparative endocrinology | ECE2008

Chemokine CXCL10 gene polymorphisms in Addison's disease

Sadet Dilek , Penna-Martinez Marissa , Kurylowicz Alina , Paunkovic Jane , Kahles Heinrich , Bruck Patrick , Badenhoop Klaus , Ramos-Lopez Elizabeth

Background and aims: CXC chemokine ligand 10 (CXCL10) also known as chemokine interferon γ inducible protein (IP-10) is a CXCR3 chemokine belongs to a group of structurally related molecules, that induce the chemotaxis of diverse leukocyte subtypes including activated T-helper 1 lymphocytes, natural killer cells and monocytes. In patients with Hashimoto’s thyroiditis, type 1 diabetes mellitus and Graves’ disease high levels of CXCL10 ligand in serum have been fo...